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1

CLEC-2 is not required for platelet aggregation at arteriolar shear

C. E. HUGHES, L. NAVARRO-NÚÑEZ, B. A. FINNEY, D. MOURÃO-SÁ, A. Y. POLLITT, S. P. WATSON

Journal:

Journal of Thrombosis and Haemostasis

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

2

Simultaneous concentration and velocity field measurements in a shock-accelerated mixing layer

Reese, Daniel, Oakley, Jason, Navarro-Nunez, Alonso, Rothamer, David, Weber, Chris, Bonazza, Riccardo

Journal:

Experiments in Fluids

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

3

CLEC-2-dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP

Borgognone, A., Navarro-Núñez, L., Correia, J. N., Pollitt, A. Y., Thomas, S. G., Eble, J. A., Pulcinelli, F. M., Madhani, M., Watson, S. P.

Journal:

Journal of Thrombosis and Haemostasis

Year:

2014

Language:

english

File:

PDF, 513 KB

english, 2014

4

Podoplanin-expressing inflammatory macrophages activate murine platelets via CLEC-2

A. M. KERRIGAN, L. NAVARRO-NUÑEZ, E. PYZ, B. A. FINNEY, J. A. WILLMENT, S. P. WATSON, G. D. BROWN

Journal:

Journal of Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 228 KB

english, 2012

5

The physiological and pathophysiological roles of platelet CLEC-2

Navarro-Núñez, L., Langan, S. A., Nash, G. B., Watson, S. P.

Journal:

Thrombosis and Haemostasis

Year:

2013

Language:

english

File:

PDF, 686 KB

english, 2013

6

THU0035 A Key Role for Platelet-Derived Clec-2 in the Regulation of Synovial Inflammation

Desanti, G.E., Naylor, A.J., Navarro-Nunez, L., Turner, J.D., Saghir, A.N., Lowe, K.L., Filer, A., Watson, S.P., Buckley, C.D.

Journal:

Annals of the Rheumatic Diseases

Year:

2015

Language:

english

File:

PDF, 96 KB

english, 2015

7

Alteraciones de las plaquetas. Etiopatogenia, clasificación, manifestaciones clínicas, diagnóstico y actitudes terapéuticas

M.L. Lozano, L. Navarro-Núñez, C. Martínez, J. Rivera

Journal:

Medicine - Programa de Formación Médica Continuada Acreditado (Elsevier España)

Year:

2008

File:

PDF, 175 KB

2008

8

Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling

Navarro-Núñez, Leyre, Y. Pollitt, Alice, Lowe, Kate, Latif, Arusa, B. Nash, Gerard, P. Watson, Steve

Journal:

Thrombosis and Haemostasis

Year:

2015

Language:

english

File:

PDF, 2.16 MB

english, 2015

9

Modulation of VEGF-induced migration and network formation by lymphatic endothelial cells: Roles of platelets and podoplanin

Langan, Stacey A., Navarro-Núñez, Leyre, Watson, Steve P., Nash, Gerard B.

Journal:

Year:

2017

Language:

english

File:

PDF, 952 KB

english, 2017

10

Platelet receptors and signaling in the dynamics of thrombus formation

Rivera, J., Lozano, M. L., Navarro-Nunez, L., Vicente, V.

Journal:

Year:

2009

Language:

english

File:

PDF, 306 KB

english, 2009

11

Platelet CLEC-2 and podoplanin in cancer metastasis

Kate L. Lowe, Leyre Navarro-Nunez, Stephen P. Watson

Journal:

Thrombosis Research

Year:

2012

Language:

english

File:

PDF, 656 KB

english, 2012

12

Syk and Src Family Kinases Regulate C-type Lectin Receptor 2 (CLEC-2)-mediated Clustering of Podoplanin and Platelet Adhesion to Lymphatic Endothelial Cells

Pollitt, A. Y., Poulter, N. S., Gitz, E., Navarro-Nunez, L., Wang, Y.-J., Hughes, C. E., Thomas, S. G., Nieswandt, B., Douglas, M. R., Owen, D. M., Jackson, D. G., Dustin, M. L., Watson, S. P.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 4.05 MB

english, 2014

13

Flavonoids inhibit the platelet TxA2 signalling pathway and antagonize TxA2 receptors (TP) in platelets and smooth muscle cells

José A. Guerrero, Leyre Navarro-Nuñez, María L. Lozano, Constantino Martínez, Vicente Vicente, Jonathan M. Gibbins, José Rivera

Journal:

British Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 370 KB

english, 2007

14

The association of the 1-tubulin Q43P polymorphism with intracerebral hemorrhage in men

Navarro-Nunez, L., Lozano, M. L., Rivera, J., Corral, J., Roldan, V., Gonzalez-Conejero, R., Iniesta, J. A., Montaner, J., Vicente, V., Martinez, C.

Journal:

Year:

2007

Language:

english

File:

PDF, 1.59 MB

english, 2007

15

JAK2 V617F, hemostatic polymorphisms, and clinical features as risk factors for arterial thrombotic events in essential thrombocythemia

María J. Moreno, María L. Lozano, V. Roldán, B. Bellosillo, N. García-Barberá, J. Rivera, L. Navarro-Núñez, C. Besses, V. Vicente, C. Martínez

Journal:

Annals of Hematology

Year:

2008

Language:

english

File:

PDF, 69 KB

english, 2008

16

[BMJ Publishing Group Ltd and European League Against Rheumatism 38th European Workshop for Rheumatology Research, 22–24 February 2018, Geneva, Switzerland - ()] Oral presentations - O014 Podoplanin (GP38), a marker of synovial inflammation, is an excellent therapeutic target in mouse collagen-induced arthritis

Desanti, GE, Saghir, AN, Naylor, AJ, Kemble, S, Falconer, J, Wehmeyer, C, Marshall, JL, Nakamura, K, Goodall, M, Navarro-Núñez, L, Watson, SP, Buckley, CD

Language:

english

File:

PDF, 73 KB

english

17

Evaluation of four rapid methods for hemoglobin screening of whole blood donors in mobile collection settings

Antonia Gómez-Simón, Leyre Navarro-Núñez, Elena Pérez-Ceballos, María L. Lozano, María J. Candela, Almudena Cascales, Constantino Martínez, Javier Corral, Vicente Vicente, José Rivera

Journal:

Transfusion and Apheresis Science

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

18

Syk-dependent Phosphorylation of CLEC-2: A NOVEL MECHANISM OF HEM-IMMUNORECEPTOR TYROSINE-BASED ACTIVATION MOTIF SIGNALING

Severin, S., Pollitt, A. Y., Navarro-Nunez, L., Nash, C. A., Mourao-Sa, D., Eble, J. A., Senis, Y. A., Watson, S. P.

Journal:

Journal of Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 1.94 MB

english, 2011

19

Between Tradition and Change: Condom Use with Primary Sexual Partners Among Mexican Migrants

Ramiro Caballero-Hoyos, Teresa Torres-Lopez, Alicia Pineda-Lucatero, Carlos Navarro-Nuñez, Raquel Fosados, Thomas W. Valente

Journal:

AIDS and Behavior

Year:

2008

Language:

english

File:

PDF, 195 KB

english, 2008

20

Differential effects of quercetin, apigenin and genistein on signalling pathways of protease-activated receptors PAR1 and PAR4 in platelets

L Navarro-Núñez, J Rivera, JA Guerrero, C Martínez, V Vicente, ML Lozano

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 396 KB

english, 2009

21

Effect of quercetin on platelet spreading on collagen and fibrinogen and on multiple platelet kinases

Leyre Navarro-Núñez, María L. Lozano, Constantino Martínez, Vicente Vicente, José Rivera

Journal:

Year:

2010

Language:

english

File:

PDF, 413 KB

english, 2010

22

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin 1 2 in Newly Formed Tertiary Lymphoid Structures

Nayar, S., Campos, J., Chung, M. M., Navarro-Nunez, L., Chachlani, M., Steinthal, N., Gardner, D. H., Rankin, P., Cloake, T., Caamano, J. H., McGettrick, H. M., Watson, S. P., Luther, S., Buckley, C.

Journal:

The Journal of Immunology

Year:

2016

Language:

english

File:

PDF, 2.26 MB

english, 2016

23

Genotype–phenotype relationship for six common polymorphisms in genes affecting platelet function from 286 healthy subjects and 160 patients with mucocutaneous bleeding of unknown cause

Constantino Martínez, Ana Isabel Antón, Javier Corral, Teresa Quiroga, Olga Panes, María Luisa Lozano, Rocío González-Conejero, Raúl Teruel, Leyre Navarro-Núñez, Jaime Pereira, Diego Mezzano, Vicente

Journal:

British Journal of Haematology

Year:

2009

Language:

english

File:

PDF, 235 KB

english, 2009

24

The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state

Lowe, Kate L., Navarro-Núñez, Leyre, Bénézech, Cécile, Nayar, Saba, Kingston, Bethany L., Nieswandt, Bernhard, Barone, Francesca, Watson, Steve P., Buckley, Christopher D., Desanti, Guillaume E.

Journal:

European Journal of Immunology

Year:

2015

Language:

english

File:

PDF, 823 KB

english, 2015

25

Apigenin Inhibits Platelet Adhesion and Thrombus Formation and Synergizes with Aspirin in the Suppression of the Arachidonic Acid Pathway

Navarro-Núñez, L., Lozano, M. L., Palomo, M., Martínez, C., Vicente, V., Castillo, J., Benavente-García, O., Diaz-Ricart, M., Escolar, G., Rivera, J.

Journal:

Journal of Agricultural and Food Chemistry

Year:

2008

Language:

english

File:

PDF, 639 KB

english, 2008

26

Protein kinase Cε and protein kinase Cθ double-deficient mice have a bleeding diathesis

A. J. UNSWORTH, B. A. FINNEY, L. NAVARRO-NUNEZ, S. SEVERIN, S. P. WATSON, C. J. PEARS

Journal:

Journal of Thrombosis and Haemostasis

Year:

2012

Language:

english

File:

PDF, 356 KB

english, 2012

27

Rare homozygous status of P43 β1-tubulin polymorphism causes alterations in platelet ultrastructure

Navarro-Núñez, L., Teruel, R., Antón, A. I., Nurden, P., Martínez-Martínez, I., Lozano, M. L., Rivera, J., Corral, J., Mezzano, D., Vicente, V., Martinez, C.

Journal:

Thrombosis and Haemostasis

Year:

2011

Language:

english

File:

PDF, 418 KB

english, 2011

28

[BMJ Publishing Group Ltd and European League Against Rheumatism 37th European Workshop for Rheumatology Research 2–4 March 2017 Athens, Greece - ()] Novel technologies - 06.16 Platelet-derived clec-2 and its ligand podoplanin (gp38) inhibit synovial inflammation

Desanti, Guillaume E, Saghir, Atif N, Naylor, Amy J, Kemble, Samuel, Marshall, Jennifer L, Falconer, Jane, Navarro-Núñez, Leyre, Watson, Stephen P, Buckley, Christopher D

Language:

english

File:

PDF, 83 KB

english

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